filterInteractionChangedFeats#

Last Updated: Jan 14, 2025

Description#

Filter Interaction Changed Feature scores.

Usage#

filterInteractionChangedFeats(
  icfObject,
  min_cells = 4,
  min_cells_expr = 1,
  min_int_cells = 4,
  min_int_cells_expr = 1,
  min_fdr = 0.1,
  min_spat_diff = 0.2,
  min_log2_fc = 0.2,
  min_zscore = 2,
  zscores_column = c("cell_type", "feats"),
  direction = c("both", "up", "down")
)

Arguments#

`icfObject`	ICF (interaction changed feature) score object
`min_cells`	minimum number of source cell type
`min_cells_expr`	minimum expression level for source cell type
`min_int_cells`	minimum number of interacting neighbor cell type
`min_int_cells_expr`	minimum expression level for interacting neighbor cell type
`min_fdr`	minimum adjusted p-value
`min_spat_diff`	minimum absolute spatial expression difference
`min_log2_fc`	minimum log2 fold-change
`min_zscore`	minimum z-score change
`zscores_column`	calculate z-scores over cell types or genes
`direction`	differential expression directions to keep

Value#

icfObject that contains the filtered differential feature scores